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TEST ID VORI Voriconazole, Serum

Reporting Name

Voriconazole, S

Specimen Type

Serum Red


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Red top (serum gel/SST not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.6 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK
 

Reference Values

1.0-5.5 mcg/mL

Trough level (ie, immediately before next dose) monitoring is recommended.

Day(s) Performed

Monday through Saturday

Report Available

Same day/1 to 2 days

Specimen Retention Time

2 weeks

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

80285

Useful For

Monitoring trough levels of voriconazole suggested for:

-Individuals with reduced liver function

-Individuals with cytochrome P450 (CYP) 2C19 alterations associated with poor metabolic function

-Patients taking other medications that affect CYP2C19 activity

-Patients experiencing potential toxicity

 

Monitoring trough levels in patients who are not responding optimally or have drug interactions that may decrease voriconazole levels or to ensure adequate oral absorption