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TEST ID TXPAB Toxoplasma gondii Antibody, IgM and IgG, Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.7 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial.


Useful For

Qualitative detection of IgM and quantitative detection of IgG antibodies to Toxoplasma gondii in human serum

Highlights

Detection of IgM-class antibodies to Toxoplasma gondii may be useful as a screen for recent infection with T gondii. Per the US Food and Drug Administration, IgM-positive results by a screening assay should be confirmed by a Toxoplasma reference laboratory. A single negative result by this assay does not rule-out toxoplasmosis as the specimen may have been collected too early following infection and prior to development of detectable antibodies.

 

An IgG only positive result indicates recent or past infection with T gondii.

Profile Information

Test ID Reporting Name Available Separately Always Performed
TXPM Toxoplasma Ab, IgM, S Yes Yes
TXPG Toxoplasma Ab, IgG, S Yes Yes

Testing Algorithm

For more information see Meningitis/Encephalitis Panel Algorithm.

Method Name

Electrochemiluminescence Immunoassay (ECLIA)

Reporting Name

Toxoplasma Ab, IgM and IgG, S

Specimen Type

Serum

Specimen Minimum Volume

0.7 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 21 days
  Frozen  90 days
  Ambient  72 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject
Additives (eg, biocides, antioxidants) Reject

Reference Values

Toxoplasma IgM

Negative

 

Toxoplasma IgG

Negative

<1 IU/mL Negative

≥1-<3 IU/mL Borderline

≥3 IU/mL Positive

 

Reference values apply to all ages.

Day(s) Performed

Monday through Saturday

Report Available

Same day/1 to 3 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86778-Toxoplasma IgM

86777-Toxoplasma IgG