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General Information

Supplies

Websites                            

Licensing and Accreditation

Mayo Clinic Laboratories

TEST ID TXMGP Toxoplasma gondii Antibody, IgM and IgG, Serum

Reporting Name

Toxoplasma Ab, IgM and IgG, S

Specimen Type

Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Aliquot tube

Specimen Volume: 1.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.8 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Testing Algorithm

For more information see Meningitis/Encephalitis Panel Algorithm

Method Name

Multiplex Flow Immunoassay (MFI)

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Heat-inactivated specimen Reject

Reference Values

Toxoplasma IgM

Negative

 

Toxoplasma IgG

Negative

 

Toxoplasma IgG Value

≤9 IU/mL (Negative)

10-11 IU/mL (Equivocal)

≥12 IU/mL (Positive)

Reference values apply to all ages.

Day(s) Performed

Monday through Friday

Report Available

Same day/1 to 3 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86778-Toxoplasma IgM

86777-Toxoplasma IgG

Forms

If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.

Useful For

Determining whether a patient has had previous exposure to or recent infection with Toxoplasma gondii

 

IgG is not useful for diagnosing infection in infants younger than 6 months of age. IgG antibodies in this age group usually are the result of passive transfer from the mother.

Highlights

Detection of IgM-class antibodies to Toxoplasma gondii may be useful as a screen for recent infection with T gondii.

 

Per the US Food and Drug Administration, IgM-positive results by a screening assay should be confirmed, for example, by a Toxoplasma reference laboratory.

 

A single negative result by this assay does not rule-out toxoplasmosis as the specimen may have been collected too early following infection, prior to development of detectable antibodies.

 

A single IgG-positive result is indicative of exposure to T gondii at some time in the past.

Profile Information

Test ID Reporting Name Available Separately Always Performed
TXM Toxoplasma Ab, IgM, S Yes Yes
TOXGP Toxoplasma Ab, IgG, S Yes Yes