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TEST ID TXMGP Toxoplasma gondii Antibody, IgM and IgG, Serum

Reporting Name

Toxoplasma Ab, IgM and IgG, S

Specimen Type

Serum


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Aliquot tube

Specimen Volume: 1.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.8 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Method Name

Multiplex Flow Immunoassay (MFI)

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Heat-inactivated specimen Reject

Reference Values

Toxoplasma IgM

Negative

 

Toxoplasma IgG

Negative

 

Toxoplasma IgG Value

≤9 IU/mL (Negative)

10-11 IU/mL (Equivocal)

≥12 IU/mL (Positive)

Reference values apply to all ages.

Day(s) Performed

Monday through Saturday

Report Available

Same day/1 to 3 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86778-Toxoplasma IgM

86777-Toxoplasma IgG

Forms

If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.

Useful For

Determining whether a patient has had previous exposure to or recent infection with Toxoplasma gondii

 

IgG is not useful for diagnosing infection in infants younger than 6 months of age. IgG antibodies in this age group usually are the result of passive transfer from the mother.

Highlights

Detection of IgM-class antibodies to Toxoplasma gondii may be useful as a screen for recent infection with T gondii.

 

Per the US Food and Drug Administration, IgM-positive results by a screening assay should be confirmed, for example, by a Toxoplasma reference laboratory.

 

A single negative result by this assay does not rule-out toxoplasmosis as the specimen may have been collected too early following infection, prior to development of detectable antibodies.

 

A single IgG-positive result is indicative of exposure to T gondii at some time in the past.

Profile Information

Test ID Reporting Name Available Separately Always Performed
TXM Toxoplasma Ab, IgM, S Yes Yes
TOXGP Toxoplasma Ab, IgG, S Yes Yes