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HelpTEST ID TPPA Syphilis Antibody, Treponema pallidum Particle Agglutination, Serum
Additional Codes
FTAr obsolete- Use TPPA
Reporting Name
Syphilis Ab by TP-PA, SSpecimen Type
SerumOrdering Guidance
This assay is recommended by the Centers for Disease Control and Prevention for sera testing positive by a screening treponemal assay and negative by rapid plasma reagin (RPR). The results of this assay assist in determining whether the results of a screening treponemal test are truly or falsely positive.
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 14 days |
Special Instructions
Testing Algorithm
For more information see Syphilis Serology Algorithm.
Method Name
Particle Agglutination
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
Reference Values
Negative
Day(s) Performed
Monday through Friday
Report Available
Same day/1 to 4 daysSpecimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
86780
Forms
If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.
Useful For
An aid to resolve discrepant results between screening treponemal and non-treponemal assays
This test is not recommended for general screening purposes for syphilis.
This test should not be used to evaluate response to therapy.
This test is not intended for medical-legal use.