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TEST ID PT217 Phospho-Tau 217, Plasma


Ordering Guidance


This assay is useful for individuals presenting with mild cognitive impairment or early dementia. Results must be interpreted in conjunction with other diagnostic tools such as neurological examination, neurobehavioral tests, imaging, and routine laboratory tests.

 

This assay should not be ordered for individuals younger than 50 years or in cognitively unimpaired individuals regardless of age.

 

This assay should not be used to predict the development of dementia or other neurologic conditions.



Specimen Required


Collection Container/Tube: Lavender top (EDTA)

Submission Container/Tube: Plastic screw-top vial

Specimen Volume: 0.6 mL

Collection Information: Centrifuge and aliquot plasma into plastic vial. Do not submit in original tube.


Useful For

Evaluation of individuals, aged 50 years and older, presenting with cognitive impairment who are being assessed for Alzheimer disease and other causes of cognitive decline

 

This test is not intended as a screening test for Alzheimer disease in asymptomatic individuals.

Method Name

Chemiluminescent Enzyme Immunoassay

Reporting Name

Phospho-Tau(217), P

Specimen Type

EDTA Plasma

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
EDTA Plasma Refrigerated (preferred) 14 days
  Frozen  90 days
  Ambient  72 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Reference Values

Negative: ≤0.185 pg/mL

Intermediate: 0.186-0.324 pg/mL

Positive: ≥0.325 pg/mL

Day(s) Performed

Monday through Friday

Report Available

1 to 3 days

Specimen Retention Time

3 months

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

84393