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TEST ID HGH Growth Hormone, Serum

Reporting Name

Growth Hormone, S

Specimen Type

Serum


Ordering Guidance


For assessing growth hormone secretion in normal children, the recommended test is IGFMS / Insulin-Like Growth Factor 1, Mass Spectrometry, Serum.

 

For acromegaly screening, the preferred test is IGFGP / Insulin-Like Growth Factor 1 and Insulin-Like Growth Factor-Binding Protein 3 Growth Panel, Serum.



Specimen Required


Patient Preparation: For at least 8 hours, patient should be fasting.

Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.6 mL

Collection Instructions:

1. If multiple specimens are collected, submit each vial under a separate order.

2. Label specimens appropriately with the corresponding collection times.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  90 days

Method Name

Immunoenzymatic Assay

Reject Due To

Gross hemolysis Reject
Gross lipemia OK

Reference Values

Males:

2-<7 years:* 0.05-5.11 ng/mL

7-<12 years:* 0.02-4.76 ng/mL

12-<14 years:* 0.01-6.20 ng/mL

14-<18 years:* 0.02-3.81 ng/mL

≥18 years: 0.01-0.97 ng/mL

 

Females:

2-<7 years:* 0.05-5.11 ng/mL

7-<12 years:* 0.02-4.76 ng/mL

12-<14 years:* 0.01-6.20 ng/mL

14-<18 years:* 0.03-5.22 ng/mL

≥18 years: 0.01-3.61 ng/mL

*Source: Karbasy K, Lin DC, Stoianov A, et al. Pediatric reference value distributions and covariate-stratified reference intervals for 29 endocrine and special chemistry biomarkers on the Beckman Coulter Immunoassay Systems: a CALIPER study of healthy community children. Clin Chem Lab Med. 2016;54(4):643-657. doi:10.1515/cclm-2015-0558

 

Reference intervals for patients younger than 2 years have not been established.

 

For International System of Units (SI) conversion for Reference Values, see www.mayocliniclabs.com/order-tests/si-unit-conversion.html

Day(s) Performed

Monday through Saturday

Report Available

1 to 3 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

83003

Forms

If not ordering electronically, complete, print, and send an Oncology Test Request (T729) with the specimen.

Useful For

Diagnosis of acromegaly and assessment of treatment efficacy when interpreted in conjunction with results from glucose suppression test

 

Diagnosis of human growth hormone deficiency when interpreted in conjunction with results from growth hormone stimulation test

 

This test is not intended for use as a screen for acromegaly.

 

This test has limited value in assessing growth hormone secretion in normal children.