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HelpTEST ID GCLIP Phospholipid (Cardiolipin) Antibodies, IgG, Serum
Reporting Name
Phospholipid Ab IgG, SSpecimen Type
SerumSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 21 days |
| Frozen | 21 days |
Method Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | OK |
| Heat-treated specimen | Reject |
Reference Values
GPL refers to IgG phospholipid units. One GPL unit is 1 microgram of IgG antibody.
Negative: <15.0 GPL)
Weakly positive: 15.0-39.9 GPL
Positive: 40.0-79.9 GPL
Strongly positive: ≥80.0 GPL
Reference values apply to all ages.
Day(s) Performed
Monday through Saturday
Report Available
Same day/1 daySpecimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
86147
Useful For
The following clinical situations, when used in conjunction with other criterial antiphospholipid antibody tests:
-Unexplained arterial or venous thrombosis
-A history of pregnancy morbidity defined as 1 or more unexplained deaths of a morphologically normal fetus beyond the 10th week of gestation, 1 or more premature births before 34 weeks of gestation caused by severe preeclampsia or placental insufficiency, or 3 or more unexplained, consecutive spontaneous abortions before the 10th week of gestation with no identifiable maternal hormonal or anatomic, or maternal or paternal chromosomal causes
-Presence of a systemic autoimmune rheumatic disease especially systemic lupus erythematosus
-Presence of an unexplained cutaneous manifestations varying from livedo reticularis to cutaneous necrosis such as leg ulcers
-Unexplained thrombocytopenia
-Possible nonbacterial, thrombotic endocarditis