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TEST ID FSCPR Scleroderma Comprehensive Profile

Reporting Name

Scleroderma Comp Profile

Specimen Type

Serum


Specimen Required


Collection Container/Tube: 10 mL Red

Submission Container/Tube: Plastic vial

Specimen Volume: 3 mL

Acceptable: SST

Collection Instructions: Draw blood in a plain red-top tube(s), serum gel tube is acceptable. Spin down and send 3 mL of serum refrigerated in a plastic vial.


Specimen Minimum Volume

1 mL (volume does not allow for repeat testing)

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  60 days
  Ambient  7 days

Testing Algorithm

If Anti-Scl-70 Ab is ≥20, Repeat Anti Scl-70 Is performed at an additional charge. If Anti-Nuclear Ab by IFA is positive, reflex test ANA Titer and Pattern is added at no additional charge.

Method Name

RIPA Gel Radiography

Immunofluorescence Antibody

Enzyme-linked immunosorbent assay (ELISA)

Reject Due To

Gross hemolysis: Reject
Thawing: Warm OK; Cold OK
Gross lipemia: Reject
Gross icterus Reject
Other: Anything other than serum; bacterial contamination

Reference Values

Anti-Nuclear Ab by IFA, Anti-U3 RNP(Fibrillarin), Anti-Th/To Ab:

Reference Range: Negative

 

Anti-Centromere Ab:

Reference Range: <1:40

 

Anti-SCL-70 Ab:

Reference Range: <20

 

Anti-RNA Polymerase III, Anti-U1RNP Ab, and Anti-PM/Scl-100 Ab:

Reference Range: <20

Negative: <20 units

Weak Positive: 20-39 units

Moderate Positive: 40-80 units

Strong Positive: >80 units

Day(s) Performed

Monday through Friday

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
FANTP ANA Titer and Pattern No No
FCA70 Repeat Anti Scl-70 No No

Report Available

14 to 25 days

Performing Laboratory

Esoterix Endocrinology

CPT Code Information

86038

83516

86235 x 5

86256