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HelpTEST ID CLPMG Phospholipid (Cardiolipin) Antibodies, IgG and IgM, Serum
Reporting Name
Phospholip Ab (Cardiolip) IgM/IgGSpecimen Type
SerumSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 21 days | |
| Frozen | 21 days |
Method Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | OK |
| Heat-treated specimen | Reject |
Reference Values
MPL refers to IgM phospholipid units. One MPL unit is 1 microgram of IgM antibody.
GPL refers to IgG phospholipid units. One GPL unit is 1 microgram of IgG antibody.
Negative: <15.0 MPL or GPL
Weakly positive: 15.0-39.9 MPL or GPL
Positive: 40.0-79.9 MPL or GPL
Strongly positive: ≥80.0 MPL or GPL
Reference values apply to all ages.
Day(s) Performed
Monday through Saturday
Report Available
Same day/1 to 2 daysSpecimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
86147 x 2
Forms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-Coagulation Test Request (T753)
-Renal Diagnostics Test Request (T830)
Useful For
The following clinical situations:
-Unexplained arterial or venous thrombosis
-A history of pregnancy morbidity defined as 1 or more unexplained deaths of a morphologically normal fetus beyond the 10th week of gestation, 1 or more premature births before 34 weeks of gestation caused by severe preeclampsia or placental insufficiency, or 3 or more unexplained, consecutive spontaneous abortions before the 10th week of gestation with no identifiable maternal hormonal or anatomic, or maternal or paternal chromosomal causes
-Presence of a systemic autoimmune rheumatic disease especially systemic lupus erythematosus
-Presence of an unexplained cutaneous manifestations varying from livedo reticularis to cutaneous necrosis such as leg ulcers
-Unexplained thrombocytopenia
-Possible nonbacterial, thrombotic endocarditis
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| MCLIP | Phospholipid Ab IgM, S | Yes | Yes |
| GCLIP | Phospholipid Ab IgG, S | Yes | Yes |