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TEST ID CCP Cyclic Citrullinated Peptide Antibodies, IgG, Serum

Important Note

This assay is intended for the detection of IgG and IgA anti-CCP3 antibodies in serum.  In conjunction with other laboratory and clinical findings, the presence may aid in the diagnosis of rheumatoid arthritis (RA), including RA diagnosed within 2 years of presentation of symptoms

 

Reporting Name

Cyclic Citrullinated Peptide Ab, S

Specimen Type

Serum


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 21 days
  Frozen  21 days

Testing Algorithm

For more information see:

-Connective Tissue Disease Cascade

-Acquired Neuropathy Diagnostic Algorithm

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK
Heat-treated specimen Reject

Reference Values

<20.0 U (negative)

20.0-39.9 U (weak positive)

40.0-59.9 U (positive)

≥60.0 U (strong positive)

Reference values apply to all ages.

Day(s) Performed

Monday through Saturday

Report Available

Same day/1 to 3 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86200

Forms

If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.

Useful For

Evaluating patients suspected of having rheumatoid arthritis (RA)

 

Differentiating RA from other inflammatory arthritis or connective tissue diseases