TEST ID AMA Mitochondrial Antibodies (M2), Serum
Test Down Notes
Effective 11/24/2025: This test is temporarily unavailable due to reagent supply issues. The downtime is expected to be 30-45 days. Order FMMA2 as an alternative. See test notification here.
Reporting Name
Mitochondrial Ab, M2, SSpecimen Type
SerumSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 21 days |
| Frozen | 21 days |
Method Name
Enzyme Immunoassay (EIA)
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | OK |
| Heat-treated specimens | Reject |
Reference Values
Negative: <0.1 Units
Borderline: 0.1-0.3 Units
Weakly positive: 0.4-0.9 Units
Positive: ≥1.0 Units
Reference values apply to all ages.
Day(s) Performed
Monday through Saturday
Report Available
2 to 3 daysSpecimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
86381
Forms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-General Request (T239)
Useful For
Establishing the diagnosis of primary biliary cholangitis
This test is not useful for indicating the stage or prognosis of the disease or for monitoring the course of the disease.